20 Questions

REMINDER!

BioLongevity Labs is running a flash Christmas sale until 10 PM PST on 12/24. Here are the details:

• Get 25% OFF ALL peptides when you buy 4 or more

• Get 25% OFF ALL bioregulators when you buy 4 or more

• Spend $1,000 or more and get invited to a private AMA webinar with Jay Campbell and me about peptides and bioregulators on Sunday, December 29

Last night, Jay and I did a live Q&A on YouTube (and everywhere else).

For those who missed it, I extracted the best questions and summarized them in today’s email for your educational reading.

Here they are:

General Peptide Use

1. Can I take Sloop (SL-PP-332) for three months straight, and should I cycle off with another mitochondrial peptide like MOTS-C or SS-31?

• Yes, you can take Sloop for three months. When cycling off, you can add in MOTS-C or SS-31 to maintain mitochondrial health. Rotating mitochondrial peptides throughout the year is a great strategy.

2. Does MK-677 help increase growth hormone, and is it worth taking?

• No, MK-677 is not recommended. While it increases growth hormone, it also elevates cortisol, prolactin, and appetite, leading to adverse side effects. Peptides like tesamorelin, ipamorelin, or CJC-1295 are better options.

3. Can I use tirzepatide for 12 weeks to lose 5 kilograms (12 pounds) of fat while maintaining muscle mass?

• Yes, but ensure you’re resistance training, hormonally optimized, supplementing minerals, and supporting your thyroid for the best results.

Female-Specific Topics

4. What can I take to increase libido besides testosterone?

• Focus on optimizing thyroid, estrogen, progesterone, and testosterone levels. Psychological and emotional factors, such as feeling secure and confident, play a significant role. A leaner body composition may also help.

5. Can women take ipamorelin and tesamorelin long-term?

• No, peptides need to be cycled to prevent antibody formation. Six- to eight-week cycles are generally recommended, especially for women over 50.

6. What testosterone levels are ideal for women?

• Total testosterone: 150–250 ng/dL.

• Free testosterone: 5–15 ng/dL.

Specific Protocols and Dosing

7. What is the best way to dose a blend of BPC-157 and TB-500 for recovery?

• Use a 1:1 blend. A typical protocol involves taking 500 mcg of each peptide in the morning and evening.

8. Can I mix 12mg of retatrutide with 2.5 ML of bac water?

• Definitely. Remember, you can always put as much or as little bac water as you want. It just depends on how much you prefer to inject.

Peptide Stacks

9. Can I stack CJC-1295 with ipamorelin as my first peptide protocol?

• Yes, this is an excellent starting stack, especially for improving muscle and fat loss. However, ensure you address hormonal deficiencies first for optimal results.

10. Can I stack Cagrilintide with tirzepatide for weight loss?

• This is only advisable for extremely overweight individuals (“dumpster fire” cases). Cagri is a potent appetite suppressant, so use it cautiously.

Side Effects and Adjustments

11. Why does Sloop increase my appetite?

• Sloop improves nutrient partitioning and raises metabolism, which can lead to increased hunger. This is normal and often indicates the peptide is working.

12. What should I do if retatrutide caused diarrhea for four days?

• This indicates a dysregulated microbiome. Work on improving gut health before trying reta again.

Advanced Topics

13. What bio-regulators or peptides help with varicose veins?

• Ventfort (a blood vessel bio-regulator) can help. Peptides like BPC-157 may also assist in healing and improving blood vessel health.

14. Can peptides be used for cancer?

• Specific peptides like PNC-27, PNC-28, and FOXO4-DRI have been studied for their potential anticancer effects. However, these are experimental and require medical supervision.

15. Do peptides like tesamorelin work less as you age?

• Yes, as IGF-1 production declines with age, growth hormone secretagogues may be less effective. Switching to pharmaceutical-grade HGH might be a better option for older individuals.

General Health and Fitness

16. How can I suppress sugar cravings?

• Use 500 mg of extended-release metformin twice daily. This helps reduce sugar cravings and improves insulin sensitivity.

17. Does BPC-157 improve GH receptor sensitivity?

• Yes, BPC-157 enhances growth hormone receptor sensitivity, making it synergistic with peptides like ipamorelin or tesamorelin.

Miscellaneous

18. What should I expect when starting ipamorelin?

• Minimal side effects. It’s well-tolerated and improves sleep, recovery, and overall well-being.

19. Is HRV affected by peptides like tirzepatide?

• Yes, tirzepatide can increase metabolic activity and resting heart rate, temporarily impacting HRV. This is normal as your body adjusts to the increased metabolism.

20. How do I join your private peptide group?

• Visit fullyoptimizedhealth.com to sign up for the membership.

I hope you are preparing for a fantastic holiday week!

Best,

Hunter