Can You Combine GLP-1 Agonists?

Everyone knows the only thing better than using one peptide is using MULTIPLE peptides at once 😁

I don’t think I need to explain this to you guys.

“Stacking” is Peptide Science 101, and something that everyone already knows (and if you’re a real beginner and don’t know that this is a thing, Peptides Demystified is the ultimate go-to resource for newbies).

With that said, anyone can stack peptides…

Stacking intelligently is a different matter.

Ultimately, it takes a certain amount of skill and knowledge to understand how to combine these agents in a way that makes sense.

And doesn’t result in you wasting your money on ineffective combinations.

So I understand why I get so many “can I combine X with Y” questions.

And one of the really interesting questions I’ve gotten is on the topic of combining GLP-1 agonists.

No, not “Can I combine tirzepatide with a growth hormone peptide like ipamorelin?” (yes, it is highly recommended to use them concurrently).

I’ve had people ask me if they can combine TWO GLP-1 agonists together.

Now, on paper, this sounds like a pretty dumb idea (or, at the very least, a wasteful idea).

After all, the major GLP-1 agonists offer INCREDIBLE appetite suppression.

Unless you’re a completely obese metabolic emergency, 2.5 - 5 mg of tirzepatide per week is more than enough to knock out hunger and cravings.

At this point, why waste your money on a second GLP-1 agonist 🤷‍♂️

Well, guess what?

This is EXACTLY what I did recently.

And it worked gangbusters 😎🔥

Here’s the story...

I recently got back from Mexico, and decided to start messing around with this.

As many of you know, I’m already a huge fan of microdosing GLP-1s…

And I thought to myself “what would happen if I microdosed with TWO at the same time?” 😏

So I combined 0.5 mg of tirzepatide and 0.5 mg of retatrutide per week…

And I felt like I was the first man to discover fire 🔥😂

Seriously, this combo is absolutely insane.

✅ It was the perfect amount of appetite suppression - without being so much that I can’t eat enough food on my training days

✅ It was the perfect amount of extra thermogenesis and fat burning - without being so much that I felt overheated

✅ And with the addition of calocurb on my fasting days, I got the perfect amount of appetite impression for that purpose (i.e. MAXIMUM 🚀)

Make sense?

I hope so.

Because when you get to the upper echelons of health optimization, fat loss and body sculpting, sometimes it’s not the AMOUNT of appetite impression that sounds, but the QUALITY.

So there ya go - my new FAVORITE GLP-1 stack.

This is something that I hammered out in last week’s AMA in the Fully Optimized Health Community, and the principles behind it are things that Jay Campbell and I cover in our Ultimate GLP-1 Masterclass (giving it away as a freebie here because I love you 😉)

No more complaining that you can’t eat enough protein or take down enough carbs on training days because you’re using the “standard” GLP-1 protocol.

👉 And in case you were unaware, both retatrutide and tirzepatide are available through Limitless Life Nootropics free VIP peptide club

But my bigger point here is this…

This magical little protocol came about because I was willing to EXPERIMENT.

This is a point that I’ve made before, but it’s worth repeating:

If you really want to get into this stuff at a high level, you MUST be willing to experiment and try different things.

Yes, be smart about it.

Yes, be informed and understand the fundamentals (one more reason to join Fully Optimized Health).

But be willing to get creative and color outside the lines…

And share your results with the rest of us 👊

Best,

Hunter Williams