Growth Hormone Peptides Vs. HGH

There are certain questions I can reliably count on to get asked at least once a month.

Many of these are basic, google-able questions like “How to reconstitute peptides.”

For elementary questions like those, I typically don’t engage.

Seriously, if you’re too lazy to Google it or too cheap to pick up a course like Peptides Demystified that will SHOW you how to do it, there’s not much hope for you.

However, many other questions I get asked do NOT fall into this category.

Many are intelligent, thoughtful inquiries that cannot be answered with a simple Google search.

One of them is the age-old question of whether to use growth hormone peptides (e.g., Ipamorelin, Tesamorelin, etc.) or actual, pharmaceutical-grade HGH.

I’ve answered this question publicly a few times (I even made a detailed video breaking it down a while back).

But to guide novices in the right direction, here’s my stance on this question.

We all know optimal growth hormone levels are critical as we age.

It’s critical for muscular development, hair, skin, and bone health, and an important pathway for optimizing fat loss…

Very few aspects of your health won’t benefit from optimizing this.

The question is not whether we should optimize it, but how.

Now, the major determining factor in choosing which route to go is your age.

As we age, a number of processes happen in the body that make producing and utilizing this vital hormone challenging.

For example, changes in the function of the liver make it much more difficult for the body to convert growth hormone into IFGF-1 (which is where we see most of the benefits of increased growth hormone).

In addition, age-related downregulation of both growth hormone and IGF-1 receptors and a decrease in serum IGF-1 levels are present.

This is important because of the differing ways in which HGH and peptides work on the body.

HGH directly supplies the body with exogenous growth hormone, while peptides endogenously raise the body’s natural levels.

In my experience, this goes a long way toward explaining why peptides can work so well for a younger individual but do next to nothing for an older individual.

This isn’t surprising.

While they’re fundamentally different hormones, this is somewhat similar to how testosterone works and why therapeutic testosterone is infinitely more effective than something like Kisspeptin.

The difference is that the testosterone apocalypse in modern civilization has left your average person with catastrophically low levels.

Kisspeptin will not even make a dent (at any age) for most individuals.

Growth hormone hasn’t been obliterated to the same degree.

This is why someone younger can “get away with” using peptides…

While an older individual will likely need to go straight to HGH.

I hope this clears up the confusion.

Best,

Hunter Williams

P.S. Curious about optimizing growth hormone levels?

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