October Q&A Video Is Up!

Happy Friday!

I just released my new Q&A video for October on Spotify.

Below, I’ve handpicked some of my favorite questions so you can skim, study, and apply immediately.

If you want the full nuance (and the questions I couldn’t fit here), make sure to watch or listen to the whole episode.

And don’t forget to submit all your questions and video suggestions to my question box.

CJC-1295 (no DAC) and Flushing

Question:

“CJC-1295 no DAC at 300 mcg gave me super flushing and a higher heart rate. Should I drop to 200 mcg for a bit?”

Answer:

Yes. That warm, flushed “rush” is common when you jump in hot with CJC. Titrate down to 150–200 mcg until your body adapts.

Many beginners do best starting with Ipamorelin alone for a week or two, then layering in CJC.

The goal is steady GH signaling without distracting side effects.

HCG + Retatrutide?

Question:

“If I’m on HCG (monotherapy) and Retatrutide, what else gives the best bang for overall wellness and fat loss?”

Answer:

Build your base, then stack.

My “simple but savage” combo would be BPC-157 + TB-500 (soft-tissue repair/inflammation), NAD+ (cellular energy), and MOTS-C (mitochondrial function/insulin sensitivity).

That covers recovery, inflammation, mitochondria, and metabolic control and pairs beautifully with HCG + Retatrutide.

If your goal is body recomp, add resistance training 3–4x/week, do cardio daily, and keep protein high. For many people, this mix unlocks better sleep, lower joint pain, and a steadier burn of visceral fat.

PTSD-type body tension

Question:

“My body subconsciously contracts at times (old PTSD), leading to pain. Is there a peptide to relax the nervous system?”

Answer:

The tool here is Selank (or N-Acetyl Selank Amidate if you need more oomph).

Dose ~1 mg once or twice daily (nasal or subQ).

Selank modulates GABAergic tone and helps the system “downshift” out of fight-or-flight.

Pair it with breath work (long exhales), magnesium glycinate or taurate in the evening, and gentle evening walks.

Trauma healing is layered.

Peptides don’t replace therapy, but Selank often takes the edge off enough for the body to unlearn the contraction pattern.

Migraines

Question:

“My friend has had migraines for years and has tried everything. Any peptide help?”

Answer:

I’ve seen SS-31 be a difference-maker.

Although the general longevity dose is 1–2 mg/day, for stubborn migraine patterns 5–10 mg/day has produced strong anecdotal wins.

Stack hydration + electrolytes, magnesium, B12, and consistent sleep timing.

If migraines are hormonally linked, address testosterone/thyroid in men and testosterone/progesterone/estradiol in women.

GLP-1s with Tesamorelin?

Question:

“Can you take a GLP-1 and Tesamorelin at the same time?”

Answer:

Yes, and it’s a power-combo.

GLP-1s improve appetite control and insulin signaling.

Tesamorelin drives GH/IGF-1 dynamics and preferential visceral-fat loss.

Together they enhance fat loss while protecting lean tissue.

GLP-1 micro-dose causing fatigue and low mood

Question:

“I’m micro-dosing Retatrutide (0.15 mg) but feel tired and a bit depressed for two days after. Ideas?”

Answer:

Three levers:

1. Hormones: low T exaggerates GLP-1 fatigue. Fix baseline.

2. Minerals: GLP-1s increase energy expenditure. Replenish magnesium + taurine.

3. Detox support: fat loss liberates stored toxins. Use injectable glutathione or Thymosin Alpha-1 for liver/immune clearance.
   

Most people adapt in 4–8 weeks.

Autoimmune disease and GLP-1s

Question:

“I’m not overweight but have autoimmune issues. Can GLP-1s still help? Is Thymosin Alpha-1 okay to start right away?”

Answer:

Yes on both.

Autoimmunity is often downstream of insulin resistance and chronic inflammation, even in normal-BMI folks with visceral fat.

GLP-1s improve insulin signaling, lower inflammatory tone, and frequently calm autoimmune flares over months.

Thymosin Alpha-1 is an excellent partner for immune modulation.

Pair with anti-inflammatory nutrition (no gluten/seed oils/sugar/dairy/alcohol), circadian-consistent sleep, and resistance training to restore insulin sensitivity.

Seasonal Flu

Question:

“Everyone’s coming down with something this time of year. What peptides do you recommend?”

Answer:

Thymosin Alpha-1, LL-37, and Thymalin/Thymogen.

Add BPC-157/TB-500 or KPV if inflammation is roaring.

Begin at first tickle in the throat and keep electrolytes, vitamin D, zinc, and sleep stress-free.

Peptides are best early and consistently dosed.

Waiting until “I’m wrecked” is a tougher road.

Timing GH peptides

Question:

“We work out at 6pm, don’t eat until 9pm. Better to inject CJC/Ipamorelin before the session or after the post-workout meal?”

Answer:

Pick one:

• Pre-workout if your stomach is relatively empty (2–3 hours since last meal).

• Pre-bed if you eat late and want to protect sleep.
  

Getting your post-workout meal in is more important than threading a needle on GH-peptide timing.

Over the long term, total compliance beats perfect timing.

If you go to bed at midnight, post-meal pre-bed dosing is great.

Otherwise, pre-workout on an emptier stomach is simple and effective.

Heart disease

Question:

“Any help for vascular blockages? VIP/Cardiogen? Is TRT safe at 72?”

Answer:

VIP and Cardiogen help the endothelium (the health of your blood vessel lining), and they belong in a cardiovascular stack.

But for outcome-level risk reduction post-event, Jardiance has the strongest data and pairs beautifully with Retatrutide for weight and inflammation control.

TRT can be appropriate at 72 and it often improves metabolic markers that drive heart risk.

Add SS-31/MOTS-C to support myocardial mitochondria.

Metformin for estrogen

Question:

“Does Metformin help lower estrogen? How long until it works?”

Answer:

It can by improving liver clearance and tamping down aromatase activity.

Expect 4–6 weeks before you see a measurable shift.

It’s gentle and won’t nuke estradiol (which you don’t want).

It fits perfectly in the “metabolic hygiene” stack alongside Jardiance/dihydroberberine.

If maximal performance is your only goal, be mindful of metformin’s tiny hit to AMPK-mTOR balance.

If healthspan + body comp are priorities, it’s a staple.

Best weight-loss GLP-1

Question:

“What’s the single best GLP-1 right now?”

Answer:

Retatrutide is king.

Best in class for fat loss and nutrient partitioning.

Appetite control is excellent for most, and with smart dosing it can support muscle building.

There’s also Orforglipron (oral) showing serious appetite suppression, and combos on the horizon.

Many lifters and bodybuilders thrive using low-dose Retatrutide with adequate carbs around training.

Final Thoughts

This captured the most relevant October questions and my answers, but it’s still just a highlight reel.

The video includes many more topics such as peptide blends, GH-peptide cramping, thyroid and hair loss in women, why I’m not bullish on SARMs, how to ship peptides without freaking out about ice packs, and timing stacks when life is busy.

👉 Watch the full October Q&A to catch every answer and nuance.

If your question didn’t make this email, submit it for November using the question box.

I read them all, and the more questions I get, the better my content for you becomes!

Best,

Hunter