Tesamorelin vs. Visceral Fat

Tesamorelin is one of the most powerful and well-researched peptides for optimizing body composition, reducing visceral fat, and improving liver health.

Despite its proven effects, most normal people walking the streets have no idea it exists.

GLP-1s get all the media coverage.

But Tesamorelin has been around for 15+ years, shredding fat off dumpster fires everywhere long before Tirz and Reta rolled onto the scene.

Today, I’ll explain exactly how Tesamorelin works, what the science says, and why it’s one of the best tools for serious biohackers looking to optimize their metabolism and longevity.

Oh, and by the way—we have Tesamorelin on sale for 15% off at BioLongevity Labs, alongside Ipamorelin, BPC-157, TB-500, BPC-157/TB-500 Blend, and Thymosin Alpha 1.

What Does the Science Say About Tesamorelin?

As an FDA-approved peptide, Tesamorelin has extensive clinical data behind it.

Here’s what the research says:

Fat Loss: Tesamorelin Specifically Targets Visceral Fat

Most fat loss methods primarily target subcutaneous fat, but Tesamorelin is one of the few compounds clinically proven to reduce visceral adipose tissue (VAT).

This is the inflammatory fat that is a threat to our well-being and longevity.

✅ After 26 weeks, Tesamorelin users saw a 15.4% reduction in visceral fat compared to placebo. The average decrease was 24 ± 41 cm², while the placebo group gained an average of 2 ± 35 cm² of VAT. (Source)

✅ After 52 weeks, total VAT reduction increased to 18%. (Source)

Remember, most of these study participants aren’t doing ANYTHING to change their diet or lifestyle, and they STILL significantly reduced their body fat.

As always, I recommend you adhere to a 30 Days 2 Shredz lifestyle to lose body fat.

Liver Fat & Fibrosis: Major Improvements in Liver Health

Tesamorelin doesn’t just cut fat—it also protects the liver.

✅ In a 12-month randomized, double-blind, placebo-controlled trial, Tesamorelin led to a 32% reduction in liver fat, while the placebo group saw a 5% increase—a net 37% improvement over placebo. (Source)

✅ Liver fibrosis progression was reduced by nearly 75%—only 10.5% of Tesamorelin users saw progression compared to 37.5% in the placebo group. (Source)

Lipid Profile Improvements: Reduced Triglycerides & Better Cholesterol Ratios

Tesamorelin doesn’t just reduce fat—it enhances lipid metabolism.

✅ Triglycerides dropped by 37 ± 139 mg/dL in the Tesamorelin group, while the placebo group increased by 6 ± 112 mg/dL—a 12.3% improvement. (Source)

✅ The cholesterol-to-HDL ratio improved by 7.2%. (Source)

What About Side Effects?

Tesamorelin has an excellent safety profile and minimal impact on glucose metabolism.

✅ After 52 weeks of use, fasting blood glucose changed by 0.00 ± 0.89 mg/dL, two-hour oral glucose tolerance test results changed by -0.08 ± 2.10 mg/dL, and fasting insulin levels decreased by 37.6 ± 180 pmol/L—indicating no significant effect on insulin resistance. (Source)

✅ Dropout rate due to adverse effects? Just 13%. Compare that to 25% in the placebo group. (Source)

Should You Use Tesamorelin?

Let’s break it down.

✅ The data is clear—Tesamorelin reduces visceral fat, liver fat, and improves lipid metabolism.

✅ It’s one of the best peptides for fat loss. Unlike GLP-1s, Tesamorelin targets deep visceral fat rather than just lowering appetite. Combined with a GLP-1 such as retatrutide, it dramatically enhances fat loss.

✅ It’s well-tolerated. Clinical trials show minimal side effects and no major impact on blood sugar regulation.

Tesamorelin is one of the best peptides available if you’re looking for a proven method to optimize fat loss, protect your liver, and enhance your metabolic health.

How to Use Tesamorelin

If you’re ready to add Tesamorelin to your protocol, here’s exactly how to reconstitute, dose, and inject it for optimal results.

Step 1: Reconstituting Tesamorelin

Your Tesamorelin vial likely comes in a 10mg vial. You’ll need to reconstitute it with bacteriostatic water before use.

✅ Use 2ml of bacteriostatic water to reconstitute your 10mg vial

✅ Allow 5-10 minutes for the peptide to become fully dissolved

Step 2: Dosing Tesamorelin Correctly

Now that your vial is mixed, here’s the math:

✅ 2mg per day is the standard clinical dose for men (I recommend 1mg for women)

✅ For a 2mg dose, withdraw 40 units into an insulin syringe. For a 1mg dose, withdraw 20 units into an insulin syringe.

✅ Inject subcutaneously into the belly fat (under the skin) before bed, ideally at least 90 minutes after your last meal.

Most users cycle Tesamorelin 8 weeks on and 8 weeks off, but if you have LOTS of fat you need to lose, I would probably suggest staying on it for 3-6 months straight.

Step 3: Managing Side Effects

✅ If you experience bloating or mild water retention, reduce the dose temporarily or take a 1-week break.

✅ Stay hydrated and monitor fasting glucose levels if necessary.

BONUS:

✅ If you have a bad reaction at the injection site (hives, itching, redness), try injecting it intramuscularly into the delts or glutes.

Where to Get Tesamorelin (And the 15% Off Sale)

If you’re serious about hacking your metabolism and taking your fat loss to the next level, Tesamorelin is currently on sale at BioLongevity Labs for 15% off.

We’re also running the 15% off sale on:

• Ipamorelin (Growth hormone secretagogue)

• BPC-157 (Gut healing & injury recovery)

• TB-500 (Tissue regeneration)

• BPC-157/TB-500 Blend (Best for healing & recovery)

• Thymosin Alpha 1 (Immune system optimization)

  

Get 15% off here (no code needed): BioLongevityLabs.com

Best,

Hunter