Why Peptides Should Be Cycled

“Hunter, do I REALLY have to cycle off my peptides??”

You’d be surprised how many times I hear this question.

Despite how many times I teach that you MUST cycle on and off these agents, many people still oppose this.

Now, for the more experienced guys reading this, you know exactly where I’m going with this:

Those first few months on any given peptide are AMAZING 🤩

It works like gangbusters.

And the best part?

It just doesn’t seem to end.

So, if you’re currently experiencing these newbie gains, I truly envy you.

And you should make the most out of it.

But here’s the thing…

It won’t last forever.

Slowly but surely, as the weeks go on, that oh-so-amazing peptide you swore would never quit will start to taper off.

This is because of the very real phenomenon of anti-body buildup and receptor attenuation.

This is basically a scientific way of saying that your body “gets used to” the peptide you’re taking.

At which point, you have two options if you want it to “keep working”:

a.) Cycle off and give your body a chance to sensitize itself

b.) Raise the dose

Do the former.

You do NOT want to get into this vicious cycle of continually raising the amount you take.

Not only will you waste a ton of money, but eventually, you WILL hit a breaking point.

Just ask the folks blasting 20 mg/week of tirzepatide and STILL not getting appetite suppression because they refused to take a breather.

I get it.

These things are AWESOME.

And if I thought there was a way to hop on them and never come off, I’d do it in a heartbeat.

But the reality is that, despite the potential of agents like low-dose naltrexone to help extend the amount of time that one can use peptides, you’ll eventually have to cycle off.

Because, as they say, what goes up must come down.

And until we find the magic bullet that will let us stay on them indefinitely, you can consider this one of the iron-clad rules of optimization.

Best,

Hunter Williams

P.S. Are you a peptide newbie?

Did this help clear up some confusion for you?

Jay Campbell and I cover all of this stuff in our Peptides Demystified Course.