Ipamorelin Use Guide

On Monday, I discussed the fantastic benefits of Tesamorelin.

While everyone can benefit from Tesamorelin, men tend to have a better response to it.

Conversely, women tend to have a slightly better response to Ipamorelin.

Today, I will discuss the amazing benefits of Ipamorelin and, more importantly — how to use it for maximum benefit.

Ipamorelin is a potent and selective growth hormone secretagogue (GHS) known for enhancing growth hormone (GH) levels without significantly affecting other hormones like cortisol.

This specificity makes it a valuable tool for improving muscle growth, fat loss, and overall metabolic health.

Oh, and by the way, BioLongevity Labs is offering 15% off Ipamorelin, Tesamorelin, BPC-157, TB-500, and Thymosin Alpha 1.

What Does the Science Say About Ipamorelin?

Ipamorelin distinguishes itself from other GHSs through its high selectivity, effectively increasing GH levels without undesired hormonal fluctuations. Here’s what the research indicates:

Growth Hormone Release

Ipamorelin stimulates GH release by binding to GHSR-1a receptors in the pituitary gland, mimicking the action of ghrelin but without significant effects on cortisol or prolactin levels.

• Selective GH Stimulation: Studies have shown that Ipamorelin increases plasma GH levels in both animals and humans without significantly altering cortisol or prolactin levels (unlike MK-677).

Muscle Growth and Fat Loss: Anabolic Effects Without Cortisol Spikes

By elevating GH levels, Ipamorelin promotes muscle anabolism and enhances fat metabolism, aiding in body recomposition efforts.

• Enhanced Muscle and Fat Metabolism: Increased GH levels from Ipamorelin administration contribute to muscle growth and fat loss.

Bone Health: Enhancing Bone Mineral Content

Ipamorelin also plays a role in supporting bone health.

• Increased Bone Mineral Content: Research indicates that Ipamorelin treatment in adult female rats increased bone mineral content and bone growth, attributed to enhanced bone dimensions without changing bone density. 

Safety and Side Effects: Minimal Impact on Other Hormones

Ipamorelin is renowned for its excellent safety profile, primarily due to its selective action on GH release without affecting other hormones.

• Hormonal Stability: Clinical studies have demonstrated that Ipamorelin does not significantly impact cortisol, ACTH, or prolactin levels, reducing the risk of hormonal imbalances.

• Potential Side Effects: While generally well-tolerated, some users may experience:

  • Metabolic Changes: Potential alterations in insulin sensitivity, necessitating caution for individuals with diabetes.

  • Injection Site Reactions: Mild swelling or irritation may occur with improper administration (if this happens, try it IM instead of subq).

  • Fatigue and Lethargy: Some users report mild fatigue due to changes in GH and metabolic activity.

Who Is It For?

Ipamorelin is particularly beneficial for individuals seeking to enhance muscle growth, promote fat loss, and support bone health.

• Women: Studies have shown that women naturally exhibit higher GH secretion rates than men at rest and during exercise. This suggests that women may experience more pronounced benefits from Ipamorelin, as their physiology is more responsive to GH fluctuations. 

• Men: While men have lower baseline GH levels, Ipamorelin effectively elevates GH without affecting other hormones, making it a valuable tool for men aiming to improve body composition and metabolic health.

How to Use Ipamorelin

If you’re ready to incorporate Ipamorelin into your regimen, here’s how to properly reconstitute, dose, and administer it for optimal results.

Step 1: Reconstituting Ipamorelin

Ipamorelin typically comes in a 10mg lyophilized powder form. To prepare it for injection:

1. Add Bacteriostatic Water: Using a sterile syringe, inject 2ml of bacteriostatic water into the vial containing the Ipamorelin powder.

2. Mix Gently: Gently swirl the vial until the powder is fully dissolved. Avoid shaking vigorously to maintain peptide integrity.

Step 2: Dosing Ipamorelin Correctly

After reconstitution, the concentration is 5mg/ml (5000mcg/ml). Recommended doses are 100-300mcg at night before bed. For precise dosing with an insulin syringe:

• 100mcg Dose: Draw up to the 2-unit mark (0.02ml) on a U-100 insulin syringe.

• 200mcg Dose: Draw up to the 4-unit mark (0.04ml).

• 300mcg Dose: Draw up to the 6-unit mark (0.06ml).

Step 3: Administering the Injection

1. Choose Injection Site: Common sites include the abdomen or thigh.

2. Clean the Area: Use an alcohol swab to disinfect the injection site.

3. Inject Subcutaneously: Pinch the skin and insert the needle at a 45-degree angle. Inject the prescribed dose slowly.

4. Rotate Sites: To prevent irritation, rotate injection sites with each administration.

If you’re serious about enhancing muscle growth, fat loss, and overall metabolic health, Ipamorelin is on sale right now at BioLongevity Labs for 15% off.

We’re also running the 15% off sale on:

• Tesamorelin – Ideal for visceral fat loss and liver health

• BPC-157 – Renowned for gut healing and injury recovery

• TB-500 – Powerful tissue regeneration and healing properties

• Thymosin Alpha 1 – Immune system optimization and modulation

If you’re ready to level up your body composition, muscle growth, and longevity, now’s the time.

Best,

Hunter